A Chicago native, Larson was one of the founding members of the Palette & Chisel Academy of Fine Arts in Chicago, and he exhibited in many of the group’s exhibitions. In later years, Larson traveled to New Orleans and produced many of his best-known images as well as his 1929 book, Sketching in New Orleans and Along the Mississippi.
Larson began his artistic career as an apprentice lithographer. He did not pursue a career in lithography, but instead took up wood engraving. Larson taught block printing to the young Gustave Baumann, who went on to make a name for himself in Nashville, Indiana, and Taos, New Mexico.
Many of Larson’s prints and paintings in watercolor and oil are scenes of New Orleans, Colorado and Michigan.